By T. H. Crook III Ph.D., G. J. Larrabee (auth.), Prof. Dr. Lüder Deecke, Prof. Dr. Peter Dal-Bianco (eds.)
The papers compiled during this supplementum are a range of the simplest con th tributions awarded on the 19 Central-European Neurological Symposium (CNS 19) hung on June 29 - July 1, 1989 in Vienna. the most subject of this convention used to be degenerative and age-associated neurological ailments. In fresh many years existence expectancy has dramatically elevated, at the least within the industrialized nations. This has resulted in severe distortions of the so-called inhabitants pyramids that now not seem like such yet start to virtually resemble cylinders. due to this "overaging" of the inhabitants, illnesses which are linked to age became even more universal than sooner than. It used to be therefore greater than average to dedicate a congress of the CNS sequence to those vital neurological ailments. the subsequent fields of curiosity are coated: Age-associated reminiscence impairment (AAMI), Alzheimer's and different dementias, Parkinson's disorder and different flow issues, stroke and others. about the de males tias, a few papers care for analysis utilizing neuro-imaging tools corresponding to MRI, CT, puppy and SPECT, others utilizing electrophysiological equipment. an enormous point within the early preclinical prognosis of dementia is the inclusion of neuropsychological assessments to reinforce the opportunity of effec tive early remedy. additionally medicines which are now lower than medical research are mentioned and initial effects are presented.
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1989b). Rosenthal fibers: Rosenthal fibers are hyaline inclusions in astrocytes, which can be found in a variety of gliomas and in especially high numbers in astrocytes of Alexander's disease. Alexander's disease is a neurodegenerative condition mostly manifesting in early age by neuropsychiatric retardation. Neuropathology is characterized by a large heavy brain and diffuse cerebral white matter destruction. Ultrastructurally Rosenthal fibers have a central amorphous core, surrounded by a periphery composed of typical intermediate filaments.
21 CPA Morphometry of the corpus callosum in normal aging and Alzheimer's disease 37 Table 2. Results of the morphometric evaluation of the human corpus callosum in normal aging and in Alzheimer's disease. 79 (31. 85 (41. 76 CPA remain unchanged (Table 2). Besides these two-dimensional parameters, further evaluations of one-dimensional parameters on callosal thickness and width have been carried out. These data showed the same trend and confirmed the above results. In summary one can say that normal aging alters mostly the frontal and temporal interhemispheric fiber systems.
Ann Neurol 25: 485-493 Fillenbaum GG, Heyman A, Wilkinson WE, Haynes CS (1987) Comparison of two screening tests in Alzheimer's disease. The correlation and reliability of the MiniMental State examination and the modified blessed test. Arch Neurol 44: 924-927 Fischer P, Gatterer G, Marterer A, Danielczyk W (1988) Nonspecificity of semantic impairment in dementia of Alzheimer's type. Arch Neurol45: 1341-1343 Fischer P, Jellinger K, Gatterer G, Marterer A, Danielczyk W (1989) Neuropathological validation of the Hachinski Scale.